Lepra Reaction
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It mostly occurs in borderline patients as well as in patients with lepromatous leprosy ll and those with tuberculoid leprosy tl receiving therapy.
Lepra reaction. Histopathology of type 1 lepra reaction shows edema within granuloma separating inflammatory cells with density of lymphocytes in the dermis. Leprosy reactions are divided into 2 types. Reversal reaction or lepra type 1 reaction is a delayed type hypersensitivity reaction that arises when borderline leprosy shifts toward borderline lepromatous leprosy with treatment.
Redirected from lepra reaction type 1 for other uses see leprosy disambiguation. These reactions may occur at any time before during or after treatment for the infection. Lepra reactions are acute inflammatory episodes that may be seen in patients with leprosy infectious agent mycobacterium leprae.
Type 1 lepra reaction reversal reaction is characterized by the development of acute erythema and swelling of existing skin lesions or by the appearance of new lesions andor neuritis 1 2. Reactions in leprosy are acute inflammatory episodes occurring in an otherwise chronic course of the infection. Type 1 reaction is a delayed hypersensitivity reaction.
Leprosy also known as hansens disease hd is a long term infection by the bacteria mycobacterium leprae or mycobacterium lepromatosis. Medical definition of lepra reaction. Lepra reaction in leprosy leprosy patients may develop certain reactions after starting the treatment and these are known as lepra reactions.
One of the acute episodes of chills and fever malaise and skin eruption occurring in the chronic course of leprosy. Type i reaction is seen in borderline tuberculoid borderline or borderline lepromatous type with worsening of skin lesions andor nerve lesions. Lepra reaction type 2 enl reaction features 6 type 2 red painful tender subcutaneous deep nodules enl appear skin commonly on the face arms and legs they appear in groups and subside within a few days even without treatment nerves may be affected but not as nerves common or severe as in type 1.
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