Lepra Reaction Type 2
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95 cases of type 2.
Lepra reaction type 2. It generally occurs in patients on treatment but may be encountered in untreated cases. Type 1 lr t1lr and type 2 lr t2lr are the major causes of nerve damage and permanent disabilities. Lepra reactions are acute inflammatory episodes that may be seen in patients with leprosy infectious agent.
Lepra reactions can be a presenting feature in a significant number of new leprosy cases at initial diagnosis. Differential diagnosis pitfalls. Slit skin smear from forehead cheek and ear lobules was negative for acid fast bacilli.
An unusual presentation abstract. Type 2 lepra reaction or erythema nodosum leprosum enl is an immune complex syndrome that occurs mostly in lepromatous leprosy and sometimes in borderline lepromatous leprosy patients. We describe unusual presentations of type 2 lepra reaction in five patients.
Skin specialist opinion was taken and was diagnosed as a case of type 2 lepra reaction and the patient was put on systemic prednisolone 1mgkgbody weight slowly tapered over 12 weeks. It is an example of type iii hypersensitivity reaction or arthus phenomenon. Ulcers with maculo papular rash are an unusual presenting feature of leprosy.
In the current scenario of leprosy elimination lepra reactions lrs remain a major persistent problem. They occur as result of. Type 2 lepra reaction is a th2 mediated type iii hypersensitivity reaction in leprosy with a characteristic cutaneous manifestation in the form of erythema nodosum leprosum enl.
Lesions less widespread than in. Type ii lepra reaction. The immunopathogenesis of lr have recently become an important field of research since it may provide the relevant targets for the early detection and control of these episodes.
Leprosy is a multi organ infectious disease affecting mainly the skin and the nerves. Ulnar nerves were the most commonly enlarged nerves in those with type 1 73 and common peroneal in type 2 65.
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