Lepra Reaction 1 Vs 2
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2 leprosy has several distinct clinical presentations depending on.
Lepra reaction 1 vs 2. The sum should be 5 that was my mnemonic. Type 1 reactions neuritis are managed with corticosteroids 2550 mgday until resolution. Leprosy also known as hansens disease hd is a long term infection by the bacteria mycobacterium leprae or mycobacterium lepromatosis.
This is a good way of remembering. This nerve damage may result in a lack of ability to feel pain which can lead to the loss of parts of a persons extremities from repeated injuries or infection due to unnoticed. Nsaids thalidomide chloroquine clofazimine corticosteroids parenteral antimony.
Ulcers with maculo papular rash are an unusual presenting feature of. Delayed hypersensitivity reaction 19 possibly immune complex deposition. Lepra reaction 1 and 2.
18 departments of medicine 1 and pathology 2 government medical college and hospital sector 32 chandigarh india. 1 the organism is thought to be transmitted from person to person via the nasal secretions of infected individuals and is known to have a long incubation period lasting 2 to 6 years. Crops of painful erythematous nodules were seen in 1920.
A chloroquin b thalidomide c cyclosporine d corticosteroids correct answer. An unusual presentation s chauhan md 1 s dcruz md dm 1 h mohan md 2 r singh md 1 j ram md 1 a sachdev md dm 1 dermatology online journal 12 1. Leprosy is a chronic granulomatous infection caused by the organism mycobacterium leprae that primarily affects the skin and peripheral nerves.
Infection can lead to damage of the nerves respiratory tract skin and eyes. Ulnar nerves were the most commonly enlarged nerves in those with type 1 73 and common peroneal in type 2 65. 95 cases of type 2.
Lepra reactions can be a presenting feature in a significant number of new leprosy cases at initial diagnosis. Cutaneous vasculitis probably due to immune complex reaction. Type 2 reactions erythema nodosum leprosum should be treated with thalidomide 100200 mgdaily clofazimine 200 mgdaily and pentoxifylline 800 mgdaily.
Second line antileprosy drugs include clarithromycin ofloxacin moxifloxacin and minocycline. Yes 1 is 4 2 is 3. Type ii lepra reaction.
Type of lepra reaction type 1 reversal reaction 14 type 2 erythema nodosum leprosum enl 15 16 lucio phenomenon 17 18 mechanism. Reversal reaction or lepra type 1 reaction is a delayed type hypersensitivity reaction that arises when borderline leprosy shifts toward borderline lepromatous leprosy with treatment. I know that lepra reaction 1 is type 4 hr and lepra reaction 2 is type 3 hr.
The following drug is not used for the treatment of type ii lepra reaction.
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