Lepra Reaction Type 1 And 2
Type 1 lr t1lr and type 2 lr t2lr are the major causes of nerve damage and permanent disabilities.
Lepra reaction type 1 and 2. Delayed hypersensitivity reaction 19 possibly immune complex deposition. Type 2 lepra reaction also known as erythema nodosum leprosum enl characteristically presents as nodules over the face arms and legs. Infection can lead to damage of the nerves respiratory tract skin and eyes.
Leprosy reactions are divided into 2 types. New tender red lumps not asso. Ulcers are an uncommon presentation of leprosy.
General condition of the patient. Lepra reactions can be a presenting feature in a significant number of new leprosy cases at initial diagnosis. Type 1 reversal and type 2 erythema nodosum leprosum reactions are the 2 main types of leprosy reactions which may affect 30 to 50 of all leprosy patients combined.
4 vasculonecrotic reactions lucio leprosy phenomenon in leprosy are much less common. Leprosy is also associated with type 1 and type 2 reactions. In the current scenario of leprosy elimination lepra reactions lrs remain a major persistent problem.
This nerve damage may result in a lack of ability to feel pain which can lead to the loss of parts of a persons extremities from repeated injuries or infection due to unnoticed. Leprosy also known as hansens disease hd is a long term infection by the bacteria mycobacterium leprae or mycobacterium lepromatosis. Type 1 lepra reaction reversal reaction is characterized by the development of acute erythema and swelling of existing skin lesions or by the appearance of new lesions andor neuritis 1 2.
Type 2 lepra reaction erythema nodosum leprosum is the appearance of skin nodules due to the immune complexmediated complication of leprosy 3. Cutaneous vasculitis probably due to immune complex reaction. Ulnar nerves were the most commonly enlarged nerves in those with type 1 73 and common peroneal in type 2 65.
95 cases of type 2. Type of lepra reaction type 1 reversal reaction 14 type 2 erythema nodosum leprosum enl 15 16 lucio phenomenon 17 18 mechanism. These occur as a result of loss of sensation peripheral or very rarely in lepra reaction both type 1 and type 2 reaction and are the presenting features of lucios phenomenon 1 2.
Crops of painful erythematous nodules were seen in 1920.