Lepra Reaction Treatment
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Lepra reaction treatment. Leprosy reactions require treatment with immunomodulatory drugs high doses of which are often required over prolonged periods and may contribute to morbidity. The who has classified two clinical scenarios multibacillary and paucibacillary cases which are very useful for treatment choosing especially treatment duration. The key drugs used to treat leprosy are dapsone rifampicin and clofazimine.
The type 1 lepra reaction is a delayed type of hypersensitivity to leprae antigens. In 6 consecutive cases of lepromatous leprosy acute severe lepra reactions were quickly resolved with disappearance of symptoms as well as signs after the use of thalidomide as a sedative. Us regimens emphasize the use of rifampin which is the most bactericidal drug used to treat leprosy.
Severe type 2 reaction may be treated with clofazimine or thalidomide. No exceptions were noted. Corticosteroids have been used to treat nerve damage associated with leprosy but a recent.
Healthcare workers dealing with patients who have leprosy reactions need to be trained in the recognition and management of the complications of immunosuppression. Concurrent therapy with sulfones and arsenicals did not appear to be involved. This type of bacteria is called a bacillus a rod shaped bacterium which causes disease.
Leprosy has several distinct clinical presentations ranging from moderate to severe with the extent of disease generally depending on the hosts immune response to the infection. This is most likely due to differences in the strength of the bodys immune response to the infection. Treatment typically involves antimicrobials eg clofazimine dapsone rifampin.
Leprosy is a bacterial infectious disorder that principally affects people in developing countries like brazil india the democratic republic of congo bangladesh and nigeria. It is clinically presumed. Clofazimine is less effective than corticosteroids and it often takes 46 weeks to be fully effective.
Leprosy is caused by bacteria called mycobacterium leprae. Clofazimine is recommended in the treatment of chronic recurrent reactions. In different people leprosy manifests in different ways.
Severe type i reactions is treated by discontinuing rifampicin therapy and high dose prednisone or clofazimine. Treatment of lepra reaction mild lepra reactions are treated with aspirin or nsaids.