What Is Lepra Reaction
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The type 1 lepra reaction is a delayed type of hypersensitivity to leprae antigens.
What is lepra reaction. These reactions account for about 3050 of cases with leprosy 2. It is a chronic communicable disease characterized by the production of granulomatous lesions of the skin mucous membranes and peripheral nervous system. Acute iritis is part of a generalized reaction known as the lepra reaction which is caused by the deposition of immune complexes in the iris.
One of the acute episodes of chills and fever malaise and skin eruption occurring in the chronic course of leprosy. It can cause severe disability prejudice and even cause blindness. Lepra reactions are of two types.
Chronic iritis is caused by m. Leprosy is a communicable disease caused by bacterium which affects the skin and peripheral nerves of people. Leprae growing in the iris causing iris atrophy.
Acute iritis is similar to other forms of acute nonleprous iritis and can lead to glaucoma and cataract. Such reactions are acute episodes which mainly affect skin and nerve and can cause death and nerve damage. The reactions manifest as acute inflammatory episodes rather than chronic infectious course 1.
Leprosy also known as hansens disease hd is a long term infection by the bacteria mycobacterium leprae or mycobacterium lepromatosis. Lepra reactions results from changes in the immune balance between host and m. This nerve damage may result in a lack of ability to feel pain which can lead to the loss of parts of a persons extremities from repeated injuries or infection due to unnoticed wounds.
Know about lepra reaction causes symptoms treatment at genericforce. Type i reaction is seen in borderline tuberculoid borderline or borderline lepromatous type with worsening of skin lesions andor nerve lesions. They can occur during the natural course of disease throughout treatment or after treatment.
Sudden changes in immune mediated response to mycobacterium leprae antigen are referred to as leprosy reactions. Lepra reaction in leprosy leprosy patients may develop certain reactions after starting the treatment and these are known as lepra reactions. Lepro se an inflammatory disease caused by mycobacterium leprae manifested in various ways depending on the hosts ability to develop cell mediated immunity.
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