Type Of Lepra Reaction
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We describe one such unusual case of a young male who presented with multiple ulcers and maculo papular rash over the legs chest and abdomen.
Type of lepra reaction. Smooth shiny diffuse thickening of facial skin ear and hand. Existing lesions show increased erythema swelling and tender peripheral nerves. Type i reaction reversal reaction it occurs due to delayed hypersensitivity and are related to cellular immune response against mycobacterial antigens.
Sudden changes in immune mediated response to mycobacterium leprae antigen are referred to as leprosy. With the leprosy patches. Type 1 reversal and type 2 erythema nodosum leprosum reactions are the 2 main types of leprosy reactions which may affect 30 to 50 of all leprosy patients combined.
Very rarely it manifests as ulcerative skin lesions. Skin type 1 reaction type 2 reaction inflammation of the skin leprosy patches are inflamed but rest of the skin normal. It mostly occurs in borderline patients as.
Lepra reactions are of two types. General condition of the patient. Loss of sensation in fingers and toes.
Some leprologists reserve the term enl for the skin lesions associated with the systemic illness of t2r. New tender red lumps not asso. Common symptoms present in the different types of leprosy include a runny nose.
Leprosy type 1 reactions t1rs also known as reversal reactions and type 2 reactions t2rs also known as erythema nodosum leprosum enl. Thickening of peripheral nerves. Two distinct types of leprosy reaction can occur.
Reversal reaction or lepra type 1 reaction is a delayed type hypersensitivity reaction that arises when borderline leprosy shifts toward borderline lepromatous leprosy with treatment. Type 1 lepra reaction reversal reaction is characterized by the development of acute erythema and swelling of existing skin lesions or by the appearance of new lesions andor neuritis 1 2. Type 1 reaction is a delayed hypersensitivity reaction.
They occur as result of neuropathy type 2 lepra reaction or lucios phenomenon. Phonation and resonation of sound during speech. A flat nose due to destruction of nasal cartilage.
However in this chapter the term enl will be used to refer to the whole syndrome. 4 vasculonecrotic reactions lucio leprosy phenomenon in leprosy are much less common. The hall mark of type 2 reaction is erythema nodosum.
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