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Lepra Multibacillary

A variety of lesions have been reported including glomerulonephritis tubulointerstitial nephritis amyloidosis acute tubular necrosis and pyelonephritis. It is more contagious. Visceral involvement is more common with multibacillary leprosy.

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In lepromatous leprosy multibacillary the host response is less pronounced and numerous bacilli can be seen within sheets of foamy histiocytes.

Lepra multibacillary. Leprae bacteria but are unable to digest the organisms who in turn multiply and use the macrophage as a method of transport throughout the body. Misclassification leads to increased risk of relapse due to insufficient treatment if a multibacillary patient is classified as paucibacillary. Classification of leprosy patients into multibacillary and paucibacillary determines the duration of their treatment.

Leprosy can be classified on the basis of clinical manifestations and skin smear results. In the multibacillary form of hansens disease tissue biopsy of various affected sites may reveal typical histopathologic changes that show large numbers of foam cells. It brings widespread skin bumps and rashes multibacillary leprosy numbness and muscle weakness.

The nose kidneys and male reproductive organs may also be affected. Leprae infection in autopsy studies. In the classification based on skin smears patients showing negative smears at all sites are grouped as paucibacillary leprosy pb while those showing positive smears at any site are grouped as having multibacillary leprosy mb.

Renal lesions can be found in up to 70 of patients with m. Foam cells are macrophages that have ingested or phagocytized m.

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